The Vへん verb ending may be the single most distinctive and recognizable piece of grammar in Kansai-ben. It is the plain non-past negative verb conjugation, analogous to Vない in standard Japanese. In addition, there is also a shortened form: Vん. Thus, standard Japanese's 行かない could be rendered as 行かへん or 行かん in Kansai-ben.

There are a variety of verb negations within the umbrella of Kansai-ben that use these two basic verb negations as a base, with variations depending on region or speaker preference.